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Kouichi Tanonaka Selected Research

YT 146

1/2015Effects of 2-Octynyladenosine (YT-146) on Mitochondrial Function in Ischemic/Reperfused Rat Hearts.
2/2011Cardioprotective effects of 2-octynyladenosine (YT-146) in ischemic/reperfused rat hearts.

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Kouichi Tanonaka Research Topics

Disease

19Ischemia
01/2015 - 06/2002
18Brain Ischemia (Cerebral Ischemia)
12/2017 - 02/2003
16Heart Failure
10/2021 - 01/2003
14Myocardial Infarction
10/2021 - 08/2003
7Fibrosis (Cirrhosis)
10/2021 - 12/2002
7Hypertrophy
10/2021 - 12/2002
6Infarction (Infarctions)
10/2021 - 02/2003
6Cardiomyopathies (Cardiomyopathy)
03/2013 - 08/2003
5Reperfusion Injury
01/2015 - 06/2002
5Embolism (Embolus)
05/2013 - 02/2003
3Mitochondrial Diseases (Mitochondrial Disease)
05/2014 - 06/2002
3Brain Injuries (Brain Injury)
05/2013 - 06/2008
3Cerebral Infarction
03/2011 - 06/2008
2Cardiomegaly (Heart Hypertrophy)
01/2019 - 12/2003
2Neurodegenerative Diseases (Neurodegenerative Disease)
05/2007 - 12/2005
2Hypoxia (Hypoxemia)
06/2003 - 06/2002
1Transient Ischemic Attack
03/2011
1Obesity
01/2011
1Hypertension (High Blood Pressure)
07/2010
1Bradycardia
08/2009
1Heart Arrest (Cardiac Arrest)
08/2009
1Brain Edema (Cerebral Edema)
12/2008
1Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome)
06/2008

Drug/Important Bio-Agent (IBA)

11Proteins (Proteins, Gene)FDA Link
10/2021 - 12/2002
6Heat-Shock Proteins (Heat-Shock Protein)IBA
03/2019 - 04/2004
6N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA
11/2012 - 12/2005
5Tyrosine (L-Tyrosine)FDA Link
11/2012 - 06/2008
3tanespimycin (17AAG)IBA
10/2021 - 01/2019
3Brain-Derived Neurotrophic Factor (BDNF)IBA
12/2017 - 03/2008
3Insulin (Novolin)FDA Link
12/2017 - 12/2002
3Small Heat-Shock ProteinsIBA
05/2014 - 01/2009
3src-Family KinasesIBA
11/2012 - 06/2008
3NADPH Oxidases (NAD(P)H oxidase)IBA
03/2011 - 10/2006
3Metabotropic Glutamate Receptors (Metabotropic Glutamate Receptor)IBA
10/2010 - 06/2008
3OccludinIBA
08/2010 - 10/2006
3Hepatocyte Growth Factor (Growth Factor, Hepatocyte)IBA
12/2008 - 10/2006
3tanshinone VIIBA
02/2008 - 12/2002
3DiterpenesIBA
02/2008 - 12/2002
3Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA
01/2007 - 04/2003
3trandolapril (Mavik)FDA LinkGeneric
01/2007 - 02/2005
3Diltiazem (Cardizem)FDA LinkGeneric
01/2006 - 02/2004
3nefiracetamIBA
03/2003 - 02/2003
3SodiumIBA
02/2003 - 07/2002
2Endothelin-1 (Endothelin 1)IBA
01/2019 - 12/2002
2YT 146IBA
01/2015 - 02/2011
2geranylgeranylacetone (teprenone)IBA
05/2014 - 01/2009
2HSP72 Heat-Shock ProteinsIBA
01/2013 - 01/2013
2Glutamic Acid (Glutamate)FDA Link
11/2012 - 10/2010
2DesminIBA
04/2011 - 01/2009
2Nerve Growth Factors (Neurotrophins)IBA
01/2011 - 03/2008
2metabotropic glutamate receptor type 1IBA
09/2010 - 06/2008
2DystrophinIBA
12/2009 - 08/2003
2N-Methylaspartate (NMDA)IBA
05/2007 - 12/2005
2Ionotropic Glutamate ReceptorsIBA
05/2007 - 12/2005
2candesartanIBA
03/2006 - 02/2005
2CalpainIBA
03/2006 - 02/2005
2Lidocaine (Xylocaine)FDA LinkGeneric
01/2006 - 05/2005
2CalciumIBA
02/2005 - 07/2002
2Adenosine Triphosphate (ATP)IBA
02/2004 - 07/2002
2Phosphates (Orthophosphate)IBA
02/2004 - 07/2002
2Vasopeptidase InhibitorsIBA
12/2003 - 04/2003
2Adenylyl Cyclases (Adenylyl Cyclase)IBA
03/2003 - 02/2003
1Therapeutic UsesIBA
05/2021
1CalcineurinIBA
01/2021
1Histone Deacetylase InhibitorsIBA
03/2019
1Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA
01/2019
1Proteasome InhibitorsIBA
01/2019
1Mitogen-Activated Protein Kinase Kinases (MEKs)IBA
01/2019
1benzyloxycarbonylleucyl-leucyl-leucine aldehydeIBA
01/2019
1chenodeoxycholate sulfate conjugate (CDCS)IBA
12/2018
1Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA
12/2017
1Aquaporin 4IBA
05/2013
1Connexin 43 (Connexin43)IBA
05/2013
1Cadherins (E-Cadherin)IBA
05/2013
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
03/2013
1Homer Scaffolding Proteins (Homer 1)IBA
04/2012
1acetovanillone (apocynin)IBA
03/2011
1Fatty Acids (Saturated Fatty Acids)IBA
01/2011
1Serine (L-Serine)FDA Link
10/2010
1Deoxycholic Acid (Sodium Deoxycholate)IBA
10/2010
1Superoxides (Superoxide)IBA
09/2010
1SC 51089IBA
08/2010
1ProstaglandinsIBA
08/2010
1Vasopressin Receptors (Arginine Vasopressin Receptor)IBA
07/2010
1SaltsIBA
07/2010
1Glycoproteins (Glycoprotein)IBA
12/2009
1MonocrotalineIBA
09/2009
1Acetylcholine (Acetylcholine Chloride)FDA Link
08/2009
1beta-CrystallinsIBA
01/2009
1Amyloid (Amyloid Fibrils)IBA
01/2009
1alpha-methyl-4-carboxyphenylglycineIBA
06/2008
1Dihydrotachysterol (AT 10)IBA
05/2008

Therapy/Procedure

11Ligation
10/2021 - 01/2003
10Microspheres (Microsphere)
12/2017 - 02/2003
3Transplantation
07/2019 - 03/2013
3Intravenous Injections
05/2013 - 01/2011
2Treatment Delay
02/2003 - 02/2003
1Cell Transplantation
12/2018
1Subcutaneous Injections
09/2009
1Intravenous Administration
06/2008